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The average age at onset is 6 to 7 years.

AS is a Takeda employee, who reviewed the study design, reviewed and interpreted data analyses, and made revisions to the manuscript.

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The term "gout" was initially used by Randolphus of Bocking, around 1200 AD.

In children, spondylolisthesis usually occurs between the fifth bone in the lower back (lumbar vertebra) and the first bone in the sacrum area.

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An increase in acute attacks of gout has been reported during the early stages of administration of Allopurinol, even when normal or subnormal serum uric acid levels have been attained.

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While the direct cause of gout is high levels of uric acid in the bloodstream, your body's ability to create and process uric acid involves many different substances.

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