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Endometriotic lesions and the associated symptoms unfortunately recur when medical treatment is discontinued and estrogen levels increase during the follicular phase of the menstrual cycle (; Wellbery).

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HIV-infected patients are also susceptible to developing thrombocytopenia for reasons unrelated to their HIV infection, such as alcohol use, splenomegaly and liver disease, or drug effects (heparin, quinidine); clinicians must always consider these possibilities when evaluating the thrombocytopenic HIV-infected patient.

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In the treatment of endometriosis, Danazol alters the normal and ectopic endometrial tissue so that it becomes inactive and atrophic.
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