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Patients with mild-to-moderate Alzheimer disease who had been randomized to galantamine therapy in previous trials received open-label continuous galantamine therapy for up to 36 months (Raskind et al 2004).

The average of a young adult with Down syndrome is 50, equivalent to the mental age of an 8- or 9-year-old child, but this can vary widely.

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Similar to galantamine, donepezil administration also produces nausea and vomiting.

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One large study used a Piaget-based theory that developed stage-based treatment plans for patients, grouped by developmental stages (Matteson et al.

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The main findings of the present study are that galantamine increases firing activity of dopaminergic cells in the VTA and, in addition, that galantamine increases dopamine output in vivo in the prefrontal cortex.

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However, clinical data suggest that while the weak AChE inhibitor galantamine has beneficial effects in schizophrenia, the more potent and specific AChE donepezil has not ().

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